Pregnancy dating criteria

The mean gestational age at delivery using US was 38.7 weeks (95%CI: 38.6–38.8), by LMP, 38.4 weeks (95%CI: 38.0–38.9), by SFH, 38.3 weeks (95%CI: 38.2–38.5), and by BS 38.0 weeks (95%CI: 37.9–38.1) (p This assessment was conducted in the framework of an open label, randomized controlled clinical trial to assess the efficacy and safety of four different artemisinin-combination therapies in women presenting with P.

falciparum malaria in the second and third trimester of pregnancy.

This included repeated measurements every first week of the month by the second trained staff member and every third week by repeated measurements of one patient.

The methods of the trial, including details on quality assurance and quality control are described in detail elsewhere [17], as well as the results of the main outcomes [16].

Since only women in the second or third trimester were eligible into the study, gestational age at enrolment was determined using diagnostic ultrasound (US) imaging equipment (FFSonic UF-4100) with a 3.5 MHz transducer for transabdominal examination normally and a 5 MHz transducer for very thin women.

We assessed the accuracy of LMP, SFH, and BS to estimate gestational age at delivery and preterm birth compared to ultrasound (US) using a large dataset derived from a randomized controlled trial in pregnant malaria patients in four African countries.

Mean and median gestational age for US, LMP, SFH and BS were calculated for the entire study population and stratified by country.

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